Endocrine Abstracts

SGLT2i drugs have been funded by the Israeli health basket since 2017 for patients with type-2-diabetes and previous cardiovascular disease, as a result of the EMPA-REG outcome studies documenting 34% reduction in all-cause mortality. In 2015 the FDA warned that SGLT2i may result in diabetic-ketoacidosis (DKA). The reported DKA cases were not typical because many had type-2-diabetes and their blood glucose was slightly increased.Objective: To describe DK...

Background: Among the various ethnicities in the Israeli mosaic, the Ethiopian community is the most recently settled, with an immigration that started less than 40 years ago. Largely young, this 160,000-member community comprises nonetheless about 25,000 persons 50 years or older, virtually all born in Ethiopia. Despite this growing aging population, there is no knowledge regarding osteoporotic fractures in this unique East African ethnic group, not even from data originating...

Objective: Israeli Ethiopian Jews (EJ) and Arabs have at reproduction age higher incidence of diabetes than other Israeli Jews. We aimed to compare gestational diabetes (GDM) risk among these population subgroups.Methods: The study cohort included age-matched EJ, non-Ethiopian Jews (NEJ) and Arab women age 20–45 years. GDM diagnosis was based on the two step screening method of 50 and 100 g oral glucose load tests. Univariate comparisons and the ass...

Introduction: Thyroid lesions with indeterminate cytology represent about 15% of all thyroid biopsies with the risk of malignancy 15–30%. So the identification of low-risk patients in this group is very important.Few studies evaluated thyroid Tc-99m MIBI [MIBI] scan as a tool for work-up of indeterminate cytology thyroid lesions. The negative predictive value of this test in excluding malignancy appears to be high (95%). But it is not used routinely...